Nightwalker: The Midnight Detective

Shido Tatsuhiko is not only a private eye... he is also a vampire with no real memory of his past. Joined by Yayoi Matsunaga, a female government agent, Riho Yamazaki, an orphaned teenage girl working as his girl Friday and Guni, a little green imp, Shido must face demonic creatures known as Nightbreed. Meanwhile, Cain, the vampire who made him what he is now, is seeking him...

(Source: Anime News Network)